The origin of nomenclature

Meyer and coworkers isolated hyaluronic acid from hyaloids of bovine eyeballs in 1934. The name, "hyaluronic acid", comes from "hyaloid" and "uronic acid", a constituent of the compound. While it is called "hyaluronan" in the international nomenclature, it is referred as "hyaluronic acid" more commonly.

K.Meyer, et al., J.Biol.Chem.,107,629 (1934)

Structure of Hyaluronic Acid

Hyaluronic acid is a linear polysaccharide formed by alternating D-glucuronic acid and N-acetyl-D-glucosamine units.

Where is hyaluronic acid found?

It is found in synovial fluid, hyaloids of eyes, skin, and umbilical cords of mammals, and also, in cockscombs.

Characteristics of Hyaluronic acid

The compound is colorless and powdery. It possesses many hydroxyl groups and shows a strong water retentivity. Its high-molecular weight nature generates a large viscosity when it is dissolved in water.

The nature of hyaluronic acid is utilized in many products, such as pharmaceuticals, cosmetics, and food.