With its increased hydrophobicity, comparing with sodium hyaluronate, sodium acetyl hyaluronate shows an improved solubility in alcohols, which makes it easier to formulate it into cosmetic products. A product containing sodium acetyl hyaluronate generally shows a non-sticky, refreshing texture.
| Solvent | HA | AcHA |
|---|---|---|
| Purified water | Very soluble | Very soluble |
| 50% Ethanol | Soluble | Very soluble |
| 80% Ethanol | Slightly soluble | Soluble |
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